Xu, J., Shi, L., Peça, J., eds. (2020). Autism Spectrum Disorder: New Insights Into Molecular Pathophysiology and Therapeutic Development. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88966-030-8

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Papers

Li Y, Lopez-Huerta VG, Adiconis X, Levandowski K, Choi S, Simmons SK, Arias-Garcia MA, Guo B, Yao AY, Blosser TR, Wimmer RD, Aida T, Atamian A, Naik T, Sun X, Bi D, Malhotra D, Hession CC, Shema R, Gomes M, Li T, Hwang E, Krol A, Kowalczyk M, Peça J, Pan G, Halassa MM, Levin JZ, Fu Z, Feng G. (2020) Distinct subnetworks of the thalamic reticular nucleus. Nature Jul 22. doi: 10.1038/s41586-020-2504-5. Epub ahead of print. PMID: 32699411.

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>>Selected Publication

Franco, L. O., Carvalho, M. J., Costa, J., Ferreira, P. A., Guedes, J. R., Sousa, R., Edfawy, M., Seabra, C. M., Cardoso, A. L., & Peça, J. (2020). Social subordination induced by early life adversity rewires inhibitory control of the prefrontal cortex via enhanced Npy1r signaling. Neuropsychopharmacology, 10.1038/s41386-020-0727-7. Advance online publication. https://doi.org/10.1038/s41386-020-0727-7

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>>Selected Publication

Barros-Viegas, A. T., Carmona, V., Ferreiro, E., Guedes, J., Cardoso, A. M., Cunha, P., Pereira de Almeida, L., Resende de Oliveira, C., Pedro de Magalhães, J., Peça, J., & Cardoso, A. L. (2020). miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer’s Disease. Molecular therapy. Nucleic acids, 19, 1219–1236. https://doi.org/10.1016/j.omtn.2020.01.010

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Luís F. Ribeiro, Tatiana Catarino, Mário Carvalho, Sandra D. Santos, Luísa Cortes, Patricio O. Opazo, Lyn Rosenbrier Ribeiro, Daniel Choquet, José A. Esteban, João Peça, Ana Luísa Carvalho (2020) Constitutive ghrelin receptor activity modulates AMPA receptor traffic and supports memory formation. bioRxiv 2020.02.05.934463; doi: https://doi.org/10.1101/2020.02.05.934463

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Catarina M Seabra, Ana Rafaela Oliveira, Joana R Guedes, Ana Luisa Cardoso, Diana B Sequeira, Paulo J Palma, Joao Miguel Santos, Frederico Duque, Guiomar Oliveira, Joao Peca (2020) Modeling the neurogenetics of neurodevelopmental disorders-hints from brain organoids. Proceedings of the 23rd Annual Meeting of the Portuguese Society of Human Genetics, Medicine: February 2020 – Volume 99 – Issue 9 – p e19291 doi: 10.1097/MD.0000000000019291

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Costa, J., Guedes, J., Ferreira, P., Franco, L., Peca, J., & Cardoso, A. L. (2019, July). Early life stress causes behaviour changes and microglia dysfunction in the pre-frontal cortex of male mice. In Glia (Vol. 67, pp. E529-E530). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.

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Rebelo, C., Pinho, S., Reis, T., Saraiva, C., Guedes, J., Bernardino, L., Peca, J. & Ferreira, L. (2019, April). NIR-light dependent delivery of Cre recombinase: an optogenetic tool for DNA modulation in the brain. In European Journal of Clinical Investigation (Vol. 49, pp. 165-165). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.

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>>Selected Publication

Edfawy, M., Guedes, J. R., Pereira, M. I., Laranjo, M., Carvalho, M. J., Gao, X., Ferreira, P. A., Caldeira, G., Franco, L. O., Wang, D., Cardoso, A. L., Feng, G., Carvalho, A. L., & Peça, J. (2019). Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice. Nature communications, 10(1), 1431. https://doi.org/10.1038/s41467-019-09382-9

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Lima Caldeira, G., Peça, J., & Carvalho, A. L. (2019). New insights on synaptic dysfunction in neuropsychiatric disorders. Current opinion in neurobiology, 57, 62–70. https://doi.org/10.1016/j.conb.2019.01.004

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Sequeira DB, Seabra CM, Palma PJ, Cardoso AL, Peça J, Santos JM. Effects of a New Bioceramic Material on Human Apical Papilla Cells. J Funct Biomater. 2018;9(4):74. Published 2018 Dec 16. doi:10.3390/jfb9040074

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Santos, T., Ferreira, R., Quartin, E., Boto, C., Saraiva, C., Bragança, J., Peça, J., Rodrigues, C., Ferreira, L., & Bernardino, L. (2017). Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles. Acta biomaterialia, 59, 293–302

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>>Selected Publication

*Ting, J. T., *Peça, J., & Feng, G. (2012). Functional consequences of mutations in postsynaptic scaffolding proteins and relevance to psychiatric disorders. Annual review of neuroscience, 35, 49-71.

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Peça, J., & Feng, G. (2012). Cellular and synaptic network defects in autism. Current opinion in neurobiology, 22(5), 866-872.

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Peça, J., Ting, J., & Feng, G. (2011). SnapShot: autism and the synapse. Cell, 147(3), 706-706.

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Peça, J., & Feng, G. (2011). When lights take the circuits out. Nature, 477(7363), 165-166.

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>> Selected Publication

Peça, J., Feliciano, C., Ting, J. T., Wang, W., Wells, M. F., Venkatraman, T. N., Lascola, C. D., Fu, Z., & Feng, G. (2011). Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature, 472(7344), 437–442. https://doi.org/10.1038/nature09965

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Heyer, M. P., Feliciano, C., Peca, J., & Feng, G. (2011). Elucidating gene function through use of genetically engineered mice. Genomics. John Wiley & Sons, Ltd, 211-248.

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Arenkiel, B. R., & Peca, J. (2009). Using light to reinstate respiratory plasticity. Journal of neurophysiology, 101(4), 1695-1698.

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Welch, J. M., Lu, J., Rodriguiz, R. M., Trotta, N. C., Peca, J., Ding, J. D., Feliciano, C., Chen, M., Adams, J. P., Luo, J., Dudek, S. M., Weinberg, R. J., Calakos, N., Wetsel, W. C., & Feng, G. (2008). [SY5. 1]: Synaptic and circuitry mechanisms of obsessive compulsive‐like behaviors in mice. International Journal of Developmental Neuroscience, 26(8), 835-835.

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>> Selected Publication

Welch, J. M., Lu, J., Rodriguiz, R. M., Trotta, N. C., Peca, J., Ding, J. D., Feliciano, C., Chen, M., Adams, J. P., Luo, J., Dudek, S. M., Weinberg, R. J., Calakos, N., Wetsel, W. C., & Feng, G. (2007). Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature, 448(7156), 894–900. https://doi.org/10.1038/nature06104

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>>Selected Publication

*Wang, H., *Peca, J., *Matsuzaki, M., Matsuzaki, K., Noguchi, J., Qiu, L., Wang, D., Zhang, F., Boyden, E., Deisseroth, K., Kasai, H., Hall, W. C., Feng, G., & Augustine, G. J. (2007). High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. PNAS, 104(19), 8143–8148. https://doi.org/10.1073/pnas.0700384104

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>>Selected Publication

Arenkiel, B. R., Peca, J., Davison, I. G., Feliciano, C., Deisseroth, K., Augustine, G. J., Ehlers, M. D., & Feng, G. (2007). In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2. Neuron, 54(2), 205–218. https://doi.org/10.1016/j.neuron.2007.03.005

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Neuronal Circuits & Behavior Laboratory

Center for Neuroscience and Cell Biology

Faculty of Medicine

University of Coimbra

Coimbra, 3004-504 – Portugal